ดร. ภานุ พิมพ์วิริยะกุล

Dr. Panu Pimviriyakul

  • Education Background

    2008-2011 B.Sc. (Chemistry), Mahidol University
    2011-2017 Ph.D. (Biochemistry), Mahidol University

  • Area of Expertise

    Protein expression and purification
    Enzyme kinetic mechanism
    Enzyme structure and function
    Enzyme engineering

  • Research Interests:

    Study of pre-steady state kinetic and protein structure of flavin-dependent enzymes.
    Development of enzyme efficiency and stability as powerful biocatalyst by enzyme engineering.

Examples
of publications

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  • Pimviriyakul, P., Wongnate, T., Tinikul, R., Chaiyen, P. (2020) Minireview: Microbial degradation of halogenated aromatics: molecular mechanisms and enzymatic reactions. Microbial Biotechnology, 13(1), 67 – 86.
  • Pongpamorn, P., Watthaisong, P., Pimviriyakul, P., Jaruwat, A., Lawan, N., Chitnumsub, P., Chaiyen, P. (2019) Identification of a hotspot residue for improving the thermostability of a flavin-dependent monooxygenase. ChemBioChem, 20(24), 3020 – 3031.
  • Watthaisong, P., Pongpamorn, P., Pimviriyakul, P., Maenpuen, S, Ohmiya, Y., Chaiyen, P. (2019) A chemo-enzymatic cascade for smart detection of nitro- and halogenated phenols. Angewandte Chemie International Edition, 58, 13254 –13258.
  • Pimviriyakul, P., Chaiyen, P. (2018) A complete bioconversion cascade for dehalogenation and denitration by bacterial flavin–dependent enzymes. Journal of Biological Chemistry, 293(48), 18525-18539.
  • Pimviriyakul, P., Surawattanawong, P., Chaiyen, P. (2018) Oxidative dehalogenation and denitration by a flavin-dependent monooxygenase is controlled by substrate deprotonation. Chemical Science, 9, 7468-7482.
  • Pimviriyakul, P., Thotsaporn, K., Sucharitakul, J., Chaiyen, P. (2017) Kinetic mechanism of the dechlorinating flavin-dependent monooxygenase HadA. Journal of Biological Chemistry, 292(12), 4818-4832.
Chapter in book
  • Pimviriyakul, P., Chaiyen, P. (2020) Overview of flavin-dependent enzymes in The Enzymes, Academic Press. 47, in press.
  • Chenprakhon, P., Pimviriyakul, , Tongsook, C, Chaiyen, P. (2020) Phenolic hydroxylases in The Enzymes, Academic Press. 47, in press.
  • Pimviriyakul, P., Chaiyen, P. (2020) Flavin-dependent dehalogenases in The Enzymes, Academic Press. 47, in press.
 
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